Calculates IV valproate sodium (valproic acid) dosing for status epilepticus and seizure management. Loading dose: 15–45 mg/kg IV at 3–6 mg/kg/min (max rate 200 mg/min). Maintenance: 10–15 mg/kg/day divided q6–8h. Monitor for thrombocytopenia, hepatotoxicity, and hyperammonemia. Contraindicated in urea cycle disorders and mitochondrial disease.
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