Von Hippel-Lindau Lesion Risk Calculator

Estimate risk of VHL-associated lesions (hemangioblastomas, ccRCC, pheochromocytoma, pancreatic NETs) based on mutation type classification (VHL type 1, 2A, 2B, 2C) and age.

Weight
Height
Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Estimate risk of VHL-associated lesions (hemangioblastomas, ccRCC, pheochromocytoma, pancreatic NETs) based on mutation type classification (VHL type 1, 2A, 2B, 2C) and age

Each component has a specific meaning:

  • Mutation type classification (VHL type 1 — The mutation type classification (vhl type 1 recorded for the scenario being assessed.
  • 2A — The 2a recorded for the scenario being assessed.
  • 2B — The 2b recorded for the scenario being assessed.
  • 2C) — The 2c) recorded for the scenario being assessed.
  • Age — The age recorded for the scenario being assessed.

Note: Interpret the vhl lesion risk result against the thresholds and context described above.

How to Use

Enter the mutation type classification (VHL type 1, 2A, 2B, 2C), age for the scenario you are assessing. Estimate risk of VHL-associated lesions (hemangioblastomas, ccRCC, pheochromocytoma, pancreatic NETs) based on mutation type classification (VHL type 1, 2A, 2B, 2C) and age. Use the vhl lesion risk result to inform your calculation.

Frequently Asked Questions