Cobalamin Disorder Classification Calculator

Classifies cobalamin (Vitamin B12) metabolism disorders (cblA-cblG, MMA, MTHFR) using methylmalonate, homocysteine, and clinical features, guiding hydroxocobalamin dosing and supplementation.

Weight
Height
Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Classifies cobalamin (Vitamin B12) metabolism disorders (cblA-cblG, MMA, MTHFR) using methylmalonate, homocysteine, and clinical features, guiding hydroxocobalamin dosing and supplementation

Each component has a specific meaning:

  • Methylmalonate — The methylmalonate recorded for the scenario being assessed.
  • Homocysteine — The homocysteine recorded for the scenario being assessed.
  • Clinical features — The clinical features recorded for the scenario being assessed.
  • Guiding hydroxocobalamin dosing — The guiding hydroxocobalamin dosing recorded for the scenario being assessed.
  • Supplementation — The supplementation recorded for the scenario being assessed.

Note: Interpret the cobalamin disorder result against the thresholds and context described above.

How to Use

Enter the methylmalonate, homocysteine, clinical features, guiding hydroxocobalamin dosing, supplementation for the scenario you are assessing. Classifies cobalamin (Vitamin B12) metabolism disorders (cblA-cblG, MMA, MTHFR) using methylmalonate, homocysteine, and clinical features, guiding hydroxocobalamin dosing and supplementation. Use the cobalamin disorder result to inform your calculation.

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Frequently Asked Questions