How does NMOSD disability differ from MS disability scoring?

NMOSD causes severe relapses with incomplete recovery, often leaving residual visual loss or paraplegia. Disability scores capture the attack-based cumulative impairment rather than progressive decline.

What biomarkers are associated with worse NMOSD outcomes?

AQP4-IgG seropositivity and MOG-IgG seropositivity are the main biomarkers. AQP4-positive NMOSD tends to have more severe attacks and greater disability accumulation than MOG-positive disease.

NMOSD Disability Score

Assess disability in Neuromyelitis Optica Spectrum Disorder using visual, motor, and sphincter domain scoring aligned with EDSS adaptation.

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Frequently Asked Questions

How does NMOSD disability differ from MS disability scoring?

What biomarkers are associated with worse NMOSD outcomes?