What are Golan OHSS grades?

Grade 1: abdominal bloating/discomfort. Grade 2: + nausea/vomiting/diarrhea, ovaries 5-12 cm. Grade 3 (moderate): + ascites on US. Grade 4 (severe): + clinical ascites/hydrothorax, ovaries >12 cm. Grade 5 (critical): + haemoconcentration (Hct >45%), coagulopathy, renal failure.

How does the freeze-all strategy prevent OHSS?

GnRH agonist trigger (instead of hCG) + freeze-all eliminates fresh embryo transfer and associated hCG from early pregnancy, preventing late OHSS. This strategy reduces severe OHSS by >80% in high-responders without compromising cumulative live birth rate.

What is the management of severe OHSS?

Hospitalization, IV albumin, paracentesis for symptomatic ascites, DVT prophylaxis (LMWH), anti-emetics, strict fluid balance. Avoid diuretics. Cabergoline 0.5 mg daily reduces OHSS through anti-VEGF mechanism.

Golan OHSS Grading and Management Score

Grade ovarian hyperstimulation syndrome (OHSS) severity using Golan classification (1-5) or RCOG/ASRM classification. Grade 3-4 (moderate-severe) with ascites and ovarian enlargement guides hospitalization and GnRH antagonist freeze-all strategy.

Use the full interactive calculator below, or

Related Calculators

IVF AFC/AMH Oocytes

Hyper-niche Medical

PCOS Rotterdam Criteria