What is a PASI 75 response?

PASI 75 = ≥75% improvement from baseline PASI. The standard efficacy endpoint in psoriasis biologic trials. PASI 90 (≥90% improvement) and PASI 100 (clear skin) are increasingly used in modern trials.

What PASI score indicates severe psoriasis?

PASI >10 with DLQI >10 indicates moderate-to-severe psoriasis qualifying for biologic therapy. BSA >10% alone or PASI >10 alone are common thresholds used across guidelines.

How are PASI body regions weighted?

Head = 10%, upper limbs = 20%, trunk = 30%, lower limbs = 40% of body surface. Each region is scored 0-72 for area × (erythema + induration + scaling). Final PASI is the weighted sum.

PASI Psoriasis Area Severity Index

Calculate PASI (Psoriasis Area and Severity Index) for plaque psoriasis. Assesses erythema, induration, and scaling in head, trunk, upper and lower limbs weighted by body surface area involvement. Standard biologic therapy endpoint.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.

How to Use

Enter the values for the scenario you are assessing. Calculate PASI (Psoriasis Area and Severity Index) for plaque psoriasis. Assesses erythema, induration, and scaling in head, trunk, upper and lower limbs weighted by body surface area involvement. Standard biologic therapy endpoint. Use the pasi psoriasis result to inform your calculation.

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