Peutz-Jeghers Syndrome Cumulative Cancer Risk Calculator

Calculate cumulative colorectal, gastric, small bowel, breast, gynaecological, and pancreatic cancer risks for STK11 (LKB1) mutation carriers with Peutz-Jeghers syndrome using age-specific penetrance data.

Weight
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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Calculate cumulative colorectal, gastric, small bowel, breast, gynaecological, and pancreatic cancer risks for STK11 (LKB1) mutation carriers with Peutz-Jeghers syndrome using age-specific penetrance data

Each component has a specific meaning:

  • Age-specific penetrance data — The age-specific penetrance data recorded for the scenario being assessed.

Note: Interpret the peutz-jeghers cancer risk result against the thresholds and context described above.

How to Use

Enter the age-specific penetrance data for the scenario you are assessing. Calculate cumulative colorectal, gastric, small bowel, breast, gynaecological, and pancreatic cancer risks for STK11 (LKB1) mutation carriers with Peutz-Jeghers syndrome using age-specific penetrance data. Use the peutz-jeghers cancer risk result to inform your calculation.

Frequently Asked Questions