Primary Immunodeficiency Disease (PID) Severity Assessment

Assesses primary immunodeficiency severity across B-cell (agammaglobulinemia, CVID), T-cell (SCID, DiGeorge), combined, and phagocyte defects to guide IVIG dosing, HSCT timing, and prophylactic antimicrobial regimens.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Assesses primary immunodeficiency severity across B-cell (agammaglobulinemia, CVID), T-cell (SCID, DiGeorge), combined, and phagocyte defects to guide IVIG dosing, HSCT timing, and prophylactic antimicrobial regimens

Each component has a specific meaning:

  • B-cell (agammaglobulinemia — The b-cell (agammaglobulinemia recorded for the scenario being assessed.
  • CVID) — The cvid) recorded for the scenario being assessed.
  • T-cell (SCID — The t-cell (scid recorded for the scenario being assessed.
  • DiGeorge) — The digeorge) recorded for the scenario being assessed.
  • Combined — The combined recorded for the scenario being assessed.
  • Phagocyte defects — The phagocyte defects recorded for the scenario being assessed.

Note: Interpret the pid severity result against the thresholds and context described above.

How to Use

Enter the B-cell (agammaglobulinemia, CVID), T-cell (SCID, DiGeorge), combined, phagocyte defects for the scenario you are assessing. Assesses primary immunodeficiency severity across B-cell (agammaglobulinemia, CVID), T-cell (SCID, DiGeorge), combined, and phagocyte defects to guide IVIG dosing, HSCT timing, and prophylactic antimicrobial regimens. Use the pid severity result to inform your calculation.

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Frequently Asked Questions