What rivaroxaban dose is recommended in AF with CrCl 15-49 mL/min?

Reduce rivaroxaban from 20 mg OD to 15 mg OD (both with evening meal) when CrCl is 15-49 mL/min for AF stroke prevention. For VTE treatment, 15 mg BD for 21 days then 20 mg OD (no CrCl adjustment needed in this range).

Is rivaroxaban used in dialysis patients?

Rivaroxaban is not recommended in ESRD (CrCl <15) or on dialysis for AF based on insufficient data. Limited pharmacokinetic studies suggest some use is possible but product labels contraindicate it in most regions.

Rivaroxaban Renal Dose Adjustment Calculator

Adjust rivaroxaban dosing for renal impairment in atrial fibrillation and VTE, reducing dose from 20 mg to 15 mg OD for AF at CrCl 15-49 and assessing contraindication thresholds below CrCl 15 mL/min.

Use the full interactive calculator below, or

Rivaroxaban Renal Dose Adjustment Calculator

Frequently Asked Questions

What rivaroxaban dose is recommended in AF with CrCl 15-49 mL/min?

Is rivaroxaban used in dialysis patients?