What mRSS score indicates severe diffuse SSc?

mRSS ≥20 indicates severe skin involvement. mRSS >20 with disease duration <2 years (early dcSSc) is the highest-risk group for internal organ involvement including renal crisis, pulmonary fibrosis, and pulmonary hypertension.

How are the 17 skin areas scored?

Each of 17 areas scored 0-3: 0=normal, 1=mild (able to tent), 2=moderate (cannot tent), 3=severe (hidebound). Areas: face, chest, abdomen, each upper arm, forearm, hand, finger, thigh, leg, foot.

What is the clinical significance of skin score peak?

mRSS typically peaks at 1-3 years in dcSSc then may plateau or slowly improve. Rapid progression in early dcSSc predicts internal organ involvement. mRSS regression during treatment does not always parallel visceral improvement.

mRSS Modified Rodnan Skin Score for Systemic Sclerosis

Calculate the modified Rodnan Skin Score (mRSS) for systemic sclerosis. Measures skin thickness in 17 areas scored 0-3. mRSS is the primary endpoint in diffuse cutaneous SSc clinical trials and predicts renal crisis risk.

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Frequently Asked Questions

What mRSS score indicates severe diffuse SSc?

How are the 17 skin areas scored?

What is the clinical significance of skin score peak?