Tuberous Sclerosis Complex Severity and mTOR Eligibility

Score tuberous sclerosis complex (TSC) organ involvement across SEGA, angiomyolipomata, pulmonary LAM, epilepsy severity, and neurodevelopmental domains to guide everolimus/sirolimus (mTORC1 inhibitor) therapy.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Score tuberous sclerosis complex (TSC) organ involvement across SEGA, angiomyolipomata, pulmonary LAM, epilepsy severity, and neurodevelopmental domains to guide everolimus/sirolimus (mTORC1 inhibitor) therapy

Each component has a specific meaning:

  • SEGA — The sega recorded for the scenario being assessed.
  • Angiomyolipomata — The angiomyolipomata recorded for the scenario being assessed.
  • Pulmonary LAM — The pulmonary lam recorded for the scenario being assessed.
  • Epilepsy severity — The epilepsy severity recorded for the scenario being assessed.
  • Neurodevelopmental domains — The neurodevelopmental domains recorded for the scenario being assessed.

Note: Interpret the tsc severity score result against the thresholds and context described above.

How to Use

Enter the SEGA, angiomyolipomata, pulmonary LAM, epilepsy severity, neurodevelopmental domains for the scenario you are assessing. Score tuberous sclerosis complex (TSC) organ involvement across SEGA, angiomyolipomata, pulmonary LAM, epilepsy severity, and neurodevelopmental domains to guide everolimus/sirolimus (mTORC1 inhibitor) therapy. Use the tsc severity score result to inform your calculation.

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