What is the New Wilson Index and transplant threshold?

New Wilson Index (NWI) = bilirubin (µmol/L)/17.1 + INR + AST/ULN + WBC (×10⁹/L)/3.5 + albumin (g/dL). Score ≥11 predicts 100% mortality without transplant (sensitivity 93%, specificity 98%).

What is the Leipzig score for Wilson disease diagnosis?

Leipzig score ≥4 = definite Wilson disease. Components: KF rings (2), neuropsychiatric symptoms (2), low Coombs-negative haemolysis (1), low serum ceruloplasmin (1–4), elevated liver copper (1–2), gene mutation analysis (0–4).

Wilson Disease Wilsons Disease Scoring (WWS/NAC Score)

Apply the Wilson Disease Severity Score (Leipzig score, New Wilson Index, NAC score) to guide diagnosis and liver transplant listing in acute Wilson disease with hepatic failure.

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Wilson Disease Wilsons Disease Scoring (WWS/NAC Score)

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Frequently Asked Questions

What is the New Wilson Index and transplant threshold?

What is the Leipzig score for Wilson disease diagnosis?