What Candida Score indicates high risk for invasive candidiasis?

Candida Score ≥3 (range 0-5): surgery + multifocal Candida colonization + total parenteral nutrition + severe sepsis; score ≥3 had 75% sensitivity for proven invasive candidiasis; consider empiric antifungal with score ≥3.

What is first-line treatment for candidemia in non-neutropenic patients?

Echinocandin (caspofungin 70 mg load + 50 mg/day, micafungin 100 mg/day, anidulafungin 200 mg load + 100 mg/day) for 14 days after last positive culture; step-down to fluconazole if fluconazole-susceptible and stable.

When can treatment step-down to fluconazole occur?

Step-down to fluconazole 400 mg/day when: Candida albicans or fluconazole-susceptible species confirmed, patient clinically stable, repeat blood cultures negative, hepatic function acceptable; usually possible at 5-7 days.

Should all patients with candidemia have ophthalmic examination?

Yes, dilated fundoscopic exam within 1 week of positive blood cultures to exclude endophthalmitis (occurs in 9-16% of candidemia); endophthalmitis extends treatment to 4-6 weeks with ophthalmology co-management.

What is the significance of species identification in candidemia?

C. krusei: inherently fluconazole-resistant (treat with echinocandin or voriconazole); C. glabrata: dose-dependent susceptibility to azoles; C. auris: pan-resistant, requires echinocandin and infection control isolation; species ID guides therapy urgently.

Candidemia Risk Score and Antifungal Treatment Calculator

Calculates Candida Score for non-neutropenic ICU patients to guide empiric antifungal therapy, and determines echinocandin dosing and step-down azole criteria based on Candida species identification.

Weight

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.

How It Works

Calculates Candida Score for non-neutropenic ICU patients to guide empiric antifungal therapy, and determines echinocandin dosing and step-down azole criteria based on Candida species identification

Each component has a specific meaning:

Candida species identification — The candida species identification recorded for the patient or scenario being assessed.

Note: Interpret the candidemia risk result against the clinical thresholds and context described above.

How to Use

Enter the Candida species identification for the patient or scenario you are assessing. Calculates Candida Score for non-neutropenic ICU patients to guide empiric antifungal therapy, and determines echinocandin dosing and step-down azole criteria based on Candida species identification. Use the candidemia risk result to inform your clinical assessment.

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