How is EASI calculated?

EASI = Σ(area × severity sum × multiplier) for 4 regions: head/neck (multiplier 0.1), upper limbs (0.2), trunk (0.3), lower limbs (0.4). Area scored 0–6; each sign 0–3. Maximum EASI = 72.

What EASI improvement is clinically meaningful?

EASI 50, EASI 75, and EASI 90 responses (50%, 75%, 90% improvement) are standard regulatory endpoints. EASI 75 is the primary endpoint for dupilumab and JAK inhibitor approvals. EASI <7 indicates mild disease.

EASI Eczema Area Severity Index

Calculate the Eczema Area and Severity Index (EASI) by scoring four body regions for area and four disease signs (erythema, edema/papulation, excoriation, lichenification) in atopic dermatitis.

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Frequently Asked Questions

How is EASI calculated?

What EASI improvement is clinically meaningful?