What Beighton score indicates generalized joint hypermobility?

Beighton ≥5/9 (adults) or ≥6/9 (children pre-puberty) or ≥4/9 (elderly) indicates GJH when associated with functional symptoms; hEDS requires GJH plus musculoskeletal features and family history.

How is autonomic dysfunction managed in hEDS?

POTS (postural orthostatic tachycardia syndrome) affects 30-40% of hEDS; compression stockings, increased fluid/salt, fludrocortisone, midodrine, or beta-blockers; pacing activities to avoid boom-bust cycle.

What physiotherapy approach helps in hEDS?

Progressive strengthening of stabilizer muscles around hypermobile joints (not stretching), proprioception training, hydrotherapy, and activity pacing; high-impact exercise and extreme ranges should be avoided.

Why is mast cell activation syndrome associated with hEDS?

The mechanistic link between MCAS and hEDS is not fully established; genetic connective tissue disorders may affect mast cell anchoring; MCAS should be screened for if urticaria, angioedema, or GI symptoms occur.

What analgesics are preferred for hEDS pain?

Duloxetine (for central sensitization), amitriptyline (low-dose for sleep and pain), NSAIDs (short-term only), and lidocaine patches; opioids should be avoided due to risk of dependence and paradoxical hypersensitivity.

Hypermobile Ehlers-Danlos Syndrome (hEDS) Diagnostic Criteria Scorer

Scores the 2017 hEDS diagnostic criteria including Beighton hypermobility score, systemic features, family history, and musculoskeletal complications to guide physiotherapy and autonomic management.

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Frequently Asked Questions

What Beighton score indicates generalized joint hypermobility?

How is autonomic dysfunction managed in hEDS?

What physiotherapy approach helps in hEDS?

Why is mast cell activation syndrome associated with hEDS?

What analgesics are preferred for hEDS pain?