Leigh Syndrome Severity Score

Score neurological severity in Leigh syndrome (subacute necrotizing encephalopathy) based on brainstem, movement, respiratory, and developmental domain impairment.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Score neurological severity in Leigh syndrome (subacute necrotizing encephalopathy) based on brainstem, movement, respiratory, and developmental domain impairment

Each component has a specific meaning:

  • Brainstem — The brainstem recorded for the scenario being assessed.
  • Movement — The movement recorded for the scenario being assessed.
  • Respiratory — The respiratory recorded for the scenario being assessed.
  • Developmental domain impairment — The developmental domain impairment recorded for the scenario being assessed.

Note: Interpret the leigh syndrome severity result against the thresholds and context described above.

How to Use

Enter the brainstem, movement, respiratory, developmental domain impairment for the scenario you are assessing. Score neurological severity in Leigh syndrome (subacute necrotizing encephalopathy) based on brainstem, movement, respiratory, and developmental domain impairment. Use the leigh syndrome severity result to inform your calculation.

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Frequently Asked Questions