What formula is used for the Roman aortic root Z-score?

Roman nomogram uses predicted aortic root diameter based on BSA (m²): predicted = 1.02 + 0.98 × BSA; Z-score = (measured - predicted) / SD; age-specific nomograms are used for children <18 years.

At what Z-score is surgical intervention considered?

Z-score ≥3 warrants close surveillance; Z-score ≥4-5 plus rapid growth or family history of dissection typically triggers elective repair; absolute diameter ≥45 mm is also an indication regardless of Z-score.

How is BSA calculated for the Z-score?

BSA (Mosteller): √(height cm × weight kg / 3600); Z-score normalization for BSA is essential in children where body size varies substantially.

How often should aortic root Z-score be monitored?

Annual echocardiogram for stable Z-score 2-4; every 6 months for Z-score >4 or growth >2 mm/year; immediately before competitive sports clearance.

What beta-blocker dose is recommended for Marfan aortopathy?

Atenolol or propranolol targeting resting HR 60-70 bpm and exercise HR <100 bpm; ARB (losartan) added for additional TGF-β blockade; combined therapy is superior to monotherapy in slowing aortic growth.

Marfan Syndrome Aortic Root Z-Score Calculator

Calculates age- and BSA-adjusted aortic root Z-score for Marfan syndrome using Roman nomogram to determine surgical urgency and monitor growth rate.

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Frequently Asked Questions

What formula is used for the Roman aortic root Z-score?

At what Z-score is surgical intervention considered?

How is BSA calculated for the Z-score?

How often should aortic root Z-score be monitored?

What beta-blocker dose is recommended for Marfan aortopathy?