Coombs Test (DAT) Interpretation for Hemolytic Anemia

Interprets the Direct Antiglobulin Test (DAT/Coombs test) results for autoimmune and alloimmune hemolytic anemia. IgG+C3d: warm AIHA; C3d alone: cold agglutinin disease; IgG alone: drug-induced or warm AIHA. Includes indirect Coombs (IAT) interpretation for pre-transfusion testing.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How to Use

Enter the values for the scenario you are assessing. Interprets the Direct Antiglobulin Test (DAT/Coombs test) results for autoimmune and alloimmune hemolytic anemia. IgG+C3d: warm AIHA; C3d alone: cold agglutinin disease; IgG alone: drug-induced or warm AIHA. Includes indirect Coombs (IAT) interpretation for pre-transfusion testing. Use the coombs test / dat result to inform your calculation.

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Frequently Asked Questions