What are Mogensen stages of diabetic nephropathy?

Stage 1: hyperfiltration (GFR elevated). Stage 2: silent (UACR normal, glomerular injury on biopsy). Stage 3: incipient (microalbuminuria 30-300 mg/g). Stage 4: overt (macroalbuminuria > 300 mg/g). Stage 5: ESRD (GFR < 15).

How can diabetic nephropathy progression be slowed?

Tight glycaemic control (HbA1c < 7%), BP control (< 130/80 with RAAS blockade), SGLT2 inhibitors (canagliflozin, empagliflozin) reduce albuminuria and delay ESRD. Finerenone reduces cardiovascular/renal outcomes in CKD with type 2 DM.

At what stage does GFR begin to decline?

GFR typically begins declining in Stage 4 (overt nephropathy). Rate of decline is approximately 10-12 mL/min/year without intervention. SGLT2 inhibitors can slow this to 2-3 mL/min/year.

Diabetic Nephropathy Mogensen Stage Calculator

Stage diabetic nephropathy using Mogensen classification (Stages 1-5) based on GFR trajectory, albuminuria, and blood pressure to guide intervention.

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Diabetic Nephropathy Mogensen Stage Calculator

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Frequently Asked Questions

What are Mogensen stages of diabetic nephropathy?

How can diabetic nephropathy progression be slowed?

At what stage does GFR begin to decline?