What is the starting EPO dose for CKD anaemia?

Epoetin alfa: 50-100 units/kg SC 3x/week; darbepoetin alfa: 0.45 mcg/kg SC weekly. Adjust dose by 25% every 4 weeks to target Hgb 10-11.5 g/dL (KDIGO guidelines).

When should ESA therapy be initiated?

Consider ESA when Hgb 11.5 g/dL due to increased cardiovascular risk.

What is ESA hyporesponsiveness?

Failure to achieve target Hgb despite EPO dose > 500 units/kg/week. Common causes: iron deficiency, infection/inflammation, hyperparathyroidism, aluminium toxicity, haemolysis.

EPO Dosing for CKD Anaemia Calculator

Calculate erythropoietin-stimulating agent (ESA) dosing for CKD-related anaemia. Initial dose: 50-100 units/kg SC 3x/week. Target Hgb 10-11.5 g/dL.

Use the full interactive calculator below, or

Related Calculators

IV Iron CKD

Medical

Kt/V Dialysis