HLH HScore for Hemophagocytic Lymphohistiocytosis

Calculate the HScore to estimate probability of reactive hemophagocytic lymphohistiocytosis using 9 variables including temperature, organomegaly, cytopenia, ferritin, fibrinogen, and bone marrow findings.

Weight
Height
Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Calculate the HScore to estimate probability of reactive hemophagocytic lymphohistiocytosis using 9 variables including temperature, organomegaly, cytopenia, ferritin, fibrinogen, and bone marrow findings

Each component has a specific meaning:

  • Organomegaly — The organomegaly recorded for the scenario being assessed.
  • Cytopenia — The cytopenia recorded for the scenario being assessed.
  • Ferritin — The ferritin recorded for the scenario being assessed.
  • Fibrinogen — The fibrinogen recorded for the scenario being assessed.
  • Bone marrow findings — The bone marrow findings recorded for the scenario being assessed.

Note: Interpret the hlh hscore result against the thresholds and context described above.

How to Use

Enter the organomegaly, cytopenia, ferritin, fibrinogen, bone marrow findings for the scenario you are assessing. Calculate the HScore to estimate probability of reactive hemophagocytic lymphohistiocytosis using 9 variables including temperature, organomegaly, cytopenia, ferritin, fibrinogen, and bone marrow findings. Use the hlh hscore result to inform your calculation.

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