Neuromuscular Blockade (NMB) Dosing for ARDS

Calculates cisatracurium dosing for neuromuscular blockade (NMB) in ARDS. Cisatracurium: 15 mg IV bolus then 37.5 mg/h (0–21 mcg/kg/min) continuous infusion for 48 hours. Indicated when PaO2/FiO2 <150 with significant ventilator dyssynchrony. ACURASYS trial showed 90-day mortality benefit; ROSE trial showed no benefit with NMB for all moderate-severe ARDS. Current guidelines: consider in severe dyssynchrony.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How to Use

Enter the values for the scenario you are assessing. Calculates cisatracurium dosing for neuromuscular blockade (NMB) in ARDS. Cisatracurium: 15 mg IV bolus then 37.5 mg/h (0–21 mcg/kg/min) continuous infusion for 48 hours. Indicated when PaO2/FiO2 <150 with significant ventilator dyssynchrony. ACURASYS trial showed 90-day mortality benefit; ROSE trial showed no benefit with NMB for all moderate-severe ARDS. Current guidelines: consider in severe dyssynchrony. Use the nmb for ards result to inform your calculation.

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