Calculates cisatracurium dosing for neuromuscular blockade (NMB) in ARDS. Cisatracurium: 15 mg IV bolus then 37.5 mg/h (0–21 mcg/kg/min) continuous infusion for 48 hours. Indicated when PaO2/FiO2 <150 with significant ventilator dyssynchrony. ACURASYS trial showed 90-day mortality benefit; ROSE trial showed no benefit with NMB for all moderate-severe ARDS. Current guidelines: consider in severe dyssynchrony.
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