NOAC Renal Dose Adjustment Calculator

Determines renal dose adjustments for NOACs. Apixaban: reduce to 2.5 mg BID if ≥2 of: age ≥80, weight ≤60 kg, creatinine ≥1.5 mg/dL. Rivaroxaban: avoid if CrCl <15 mL/min (AF); use with caution CrCl 15–30. Dabigatran: avoid if CrCl <30; reduce to 75 mg BID if CrCl 15–30 (US label). Edoxaban: 30 mg daily if CrCl 15–50 mL/min.