Calculate systemic oxygen delivery: DO2 = CO x CaO2 x 10. CaO2 = (Hb x 1.34 x SaO2) + (PaO2 x 0.0031). Normal DO2 = 950-1150 mL/min. CO in L/min, Hb in g/dL, SaO2 as fraction (0-1). Critical threshold: DO2 < 330 mL/min (anaerobic threshold).
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