How is the SOFA score calculated?

Each organ system scored 0 to 4: Respiratory (PaO2/FiO2 ratio), Coagulation (platelet count), Liver (bilirubin), Cardiovascular (vasopressor use and dose), CNS (GCS), Renal (creatinine or urine output). Total 0 to 24. SOFA >=2: >10% ICU mortality. SOFA 8 to 11: approximately 40%. SOFA >11: >95% mortality. Serial SOFA (delta SOFA) tracks trajectory.

What is the difference between baseline and delta SOFA?

Baseline SOFA: absolute organ failure burden at a time point. Delta SOFA: change in score over 24 to 48 hours - more prognostically important than absolute score. Increasing SOFA over 48h is associated with >50% ICU mortality regardless of absolute score. Decreasing SOFA indicates response to treatment. SOFA used in Sepsis-3 criteria definition.

SOFA Sequential Organ Failure Assessment Score

Calculate daily SOFA score assessing 6 organ systems (respiratory, coagulation, liver, cardiovascular, CNS, renal) to quantify organ dysfunction, predict ICU mortality, and monitor treatment response.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.

How to Use

Enter the values for the scenario you are assessing. Calculate daily SOFA score assessing 6 organ systems (respiratory, coagulation, liver, cardiovascular, CNS, renal) to quantify organ dysfunction, predict ICU mortality, and monitor treatment response. Use the sofa score result to inform your calculation.

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