What PASI score indicates severe psoriasis?

PASI >=10 with DLQI >10 defines moderate-to-severe psoriasis qualifying for biologic therapy per EuroGuiDerm 2023. PASI >=12 indicates severe disease. PASI 75 (75% reduction) is the standard biologic efficacy endpoint.

What is PASI 75, 90, and 100?

PASI 75: >=75% reduction from baseline (minimum acceptable biologic response). PASI 90: >=90% reduction (standard target for modern biologics). PASI 100: complete clearance (achievable with IL-17, IL-23 inhibitors in 40-60% of patients).

How is the PASI score calculated?

Each body region is scored: severity (erythema+induration+desquamation, 0-12) x area (0-6). Multiplied by region weight (head 0.1, arms 0.2, trunk 0.3, legs 0.4). Maximum PASI = 72.

PASI Psoriasis Area Severity Index

Calculate the Psoriasis Area and Severity Index (PASI) across four body regions (head, trunk, upper, lower extremities): erythema, induration, desquamation (0-4 each) x area (0-6 each). Range 0-72.

Use the full interactive calculator below, or

PASI Psoriasis Area Severity Index

Frequently Asked Questions

What PASI score indicates severe psoriasis?

What is PASI 75, 90, and 100?

How is the PASI score calculated?