SLEDAI-2K — SLE Disease Activity Index

Calculates the SLE Disease Activity Index 2000 (SLEDAI-2K), a weighted 24-item score assessing SLE disease activity across neurological, vascular, renal, musculoskeletal, serosal, skin, immunological, and constitutional domains. Scores >20 indicate very high activity.

Weight
Height
Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Calculates the SLE Disease Activity Index 2000 (SLEDAI-2K), a weighted 24-item score assessing SLE disease activity across neurological, vascular, renal, musculoskeletal, serosal, skin, immunological, and constitutional domains. Scores >20 indicate very high activity

Each component has a specific meaning:

  • Neurological — The neurological recorded for the scenario being assessed.
  • Vascular — The vascular recorded for the scenario being assessed.
  • Renal — The renal recorded for the scenario being assessed.
  • Musculoskeletal — The musculoskeletal recorded for the scenario being assessed.
  • Serosal — The serosal recorded for the scenario being assessed.
  • Skin — The skin recorded for the scenario being assessed.

Note: Interpret the sledai-2k result against the thresholds and context described above.

How to Use

Enter the neurological, vascular, renal, musculoskeletal, serosal, skin for the scenario you are assessing. Calculates the SLE Disease Activity Index 2000 (SLEDAI-2K), a weighted 24-item score assessing SLE disease activity across neurological, vascular, renal, musculoskeletal, serosal, skin, immunological, and constitutional domains. Scores >20 indicate very high activity. Use the sledai-2k result to inform your calculation.

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Frequently Asked Questions