Hydrocortisone Threshold for Septic Shock Steroids

Determines when hydrocortisone should be initiated in septic shock. Indication: hemodynamic instability despite adequate fluid resuscitation AND vasopressor therapy. Dose: hydrocortisone 200 mg/day IV (50 mg q6h or 200 mg/day continuous infusion). Taper over 5–7 days when vasopressors are discontinued. Do not use low-dose hydrocortisone in patients who are NOT vasopressor-dependent.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How to Use

Enter the values for the scenario you are assessing. Determines when hydrocortisone should be initiated in septic shock. Indication: hemodynamic instability despite adequate fluid resuscitation AND vasopressor therapy. Dose: hydrocortisone 200 mg/day IV (50 mg q6h or 200 mg/day continuous infusion). Taper over 5–7 days when vasopressors are discontinued. Do not use low-dose hydrocortisone in patients who are NOT vasopressor-dependent. Use the steroids in septic shock result to inform your calculation.

Frequently Asked Questions