Determines when hydrocortisone should be initiated in septic shock. Indication: hemodynamic instability despite adequate fluid resuscitation AND vasopressor therapy. Dose: hydrocortisone 200 mg/day IV (50 mg q6h or 200 mg/day continuous infusion). Taper over 5–7 days when vasopressors are discontinued. Do not use low-dose hydrocortisone in patients who are NOT vasopressor-dependent.
Use the full interactive calculator below, or