What 25(OH)D level is considered sufficient?

30-100 ng/mL (75-250 nmol/L) is considered sufficient for most people. Levels 20-29 ng/mL are insufficient for optimal bone health. Levels below 20 ng/mL are deficient. Most experts agree levels above 50 ng/mL provide no additional benefit.

What is the treatment dose for vitamin D deficiency?

For deficiency (below 20 ng/mL): 50,000 IU vitamin D3 weekly for 8-12 weeks, then maintenance 1500-2000 IU/day. For insufficiency: 800-1000 IU/day may suffice. Sun exposure and dietary sources rarely achieve adequate levels.

What factors affect vitamin D levels?

Factors reducing vitamin D: darker skin pigmentation, minimal sun exposure, obesity (fat sequestration), malabsorption disorders, kidney disease (impaired activation), liver disease (impaired 25-hydroxylation), and certain medications (anticonvulsants, rifampicin).

Vitamin D Status Thresholds

Classify vitamin D status by 25(OH)D level: deficient below 20 ng/mL (below 50 nmol/L), insufficient 20-29 ng/mL, sufficient 30-100 ng/mL, potential toxicity above 100 ng/mL. Replacement dose: 1000-2000 IU/day maintenance.

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Frequently Asked Questions

What 25(OH)D level is considered sufficient?

What is the treatment dose for vitamin D deficiency?

What factors affect vitamin D levels?