Warfarin CYP2C9 Genotype Dose Adjustment

Adjust warfarin dose based on CYP2C9 metabolizer phenotype. *1/*1 normal, *1/*2 or *1/*3 reduce by 10-25%, *2/*3 or *3/*3 reduce by 40-70%.

Weight
Height
Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
Advertisement

How It Works

Adjust warfarin dose based on CYP2C9 metabolizer phenotype. *1/*1 normal, *1/*2 or *1/*3 reduce by 10-25%, *2/*3 or *3/*3 reduce by 40-70%

Each component has a specific meaning:

  • CYP2C9 metabolizer phenotype — The cyp2c9 metabolizer phenotype recorded for the scenario being assessed.

Note: Interpret the warfarin cyp2c9 result against the thresholds and context described above.

How to Use

Enter the CYP2C9 metabolizer phenotype for the scenario you are assessing. Adjust warfarin dose based on CYP2C9 metabolizer phenotype. *1/*1 normal, *1/*2 or *1/*3 reduce by 10-25%, *2/*3 or *3/*3 reduce by 40-70%. Use the warfarin cyp2c9 result to inform your calculation.

Related Calculators

Warfarin VKORC1

Medical Ultra-depth

Frequently Asked Questions