Warfarin VKORC1 Variant Sensitivity Calculator

Estimate warfarin sensitivity from VKORC1 haplotype. -1639A/A haplotype confers high sensitivity; reduce dose 30-50% vs G/G.

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Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.
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How It Works

Estimate warfarin sensitivity from VKORC1 haplotype. -1639A/A haplotype confers high sensitivity; reduce dose 30-50% vs G/G

Each component has a specific meaning:

  • VKORC1 haplotype — The vkorc1 haplotype recorded for the scenario being assessed.

Note: Interpret the warfarin vkorc1 result against the thresholds and context described above.

How to Use

Enter the VKORC1 haplotype for the scenario you are assessing. Estimate warfarin sensitivity from VKORC1 haplotype. -1639A/A haplotype confers high sensitivity; reduce dose 30-50% vs G/G. Use the warfarin vkorc1 result to inform your calculation.

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