PGA is typically recorded on a 0–10 or 0–100 mm VAS, or a 0–4 Likert scale, where 0 = no disease activity and the maximum = most severe disease activity possible. It captures the clinician's overall assessment of disease status.

When is PGA used as a primary outcome?

PGA is used as both a standalone measure and a component of composite scores (DAS28, CDAI, SDAI, BDCAF, ESSDAI). As a primary endpoint, it is required for FDA/EMA approval in many rheumatological conditions.

Physician Global Assessment Score

Record the Physician Global Assessment (PGA) of disease activity on a visual analogue or Likert scale, used across rheumatology, dermatology, and gastroenterology to capture overall clinical impression.

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Frequently Asked Questions

How is PGA measured?

When is PGA used as a primary outcome?