What defines septic shock under Sepsis-3?

Septic shock requires vasopressor requirement to maintain MAP ≥65 mmHg AND serum lactate >2 mmol/L (>18 mg/dL) despite adequate fluid resuscitation, carrying hospital mortality >40%.

How did Sepsis-3 change the definition of severe sepsis?

Sepsis-3 eliminated the 'severe sepsis' category. What was previously severe sepsis is now simply 'sepsis', while the more severe 'septic shock' definition now requires both vasopressor need and hyperlactatemia.

Sepsis-3 Criteria Checker — Sepsis and Septic Shock

Apply the Sepsis-3 definitions to identify sepsis (suspected infection + SOFA increase ≥2) and septic shock (vasopressors needed for MAP ≥65 with lactate >2 mmol/L) for early intervention.

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SOFA Score

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Sepsis-3 Criteria Checker — Sepsis and Septic Shock

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Frequently Asked Questions

What defines septic shock under Sepsis-3?

How did Sepsis-3 change the definition of severe sepsis?