What are the 2011 ACR/EULAR Boolean remission criteria?

Boolean remission requires ALL of: TJC28 ≤1, SJC28 ≤1, CRP ≤1 mg/dL (10 mg/L), and PGA ≤20/100 mm; all four criteria must be simultaneously met at each visit; SDAI ≤3.3 is an equivalent index-based definition.

Why is PGA a challenging criterion for Boolean remission?

PGA (patient global assessment of disease activity) is often elevated above 20 mm even with well-controlled synovitis due to pain, fatigue, and comorbidities; PGA ≤20 mm is frequently the most difficult Boolean criterion to achieve.

How does imaging define remission vs clinical criteria?

Power Doppler ultrasound can detect subclinical synovitis in patients in clinical (DAS28/Boolean) remission; ultrasound remission correlates better with subsequent radiographic progression prevention; imaging remission is the aspirational T2T target.

What is the EULAR remission recommendation for biologic tapering?

Sustained remission (usually ≥6-12 months on biologic) is required before tapering; taper by spacing injection intervals before dose reduction; monitoring interval increases after tapering; flare rate on tapering is 20-40%.

Can RA remission be achieved without methotrexate?

MTX remains the anchor DMARD for most RA patients; MTRA data shows higher remission rates with MTX-based combinations; JAK inhibitors as monotherapy show similar efficacy to combination biologics in MTX-intolerant patients; MTX-free T2T is feasible with JAK inhibitors.

ACR/EULAR Boolean Remission Criteria for Rheumatoid Arthritis

Applies 2011 ACR/EULAR Boolean remission criteria for rheumatoid arthritis (TJC28 ≤1, SJC28 ≤1, CRP ≤1 mg/dL, PGA ≤20 mm) and calculates SDAI remission as an alternative index-based definition.

Weight

Height

Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.

How to Use

Enter the values for the patient or scenario you are assessing. Applies 2011 ACR/EULAR Boolean remission criteria for rheumatoid arthritis (TJC28 ≤1, SJC28 ≤1, CRP ≤1 mg/dL, PGA ≤20 mm) and calculates SDAI remission as an alternative index-based definition. Use the acr/eular remission result to inform your clinical assessment.

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