APACHE III Score — Acute Physiology and Chronic Health Evaluation III

Calculate the APACHE III score, an ICU severity-of-illness measure that sums acute physiology points across 17 variables, an age modifier, and chronic health/comorbidity flags. Total score ranges 0–299, with higher scores indicating greater physiologic derangement and higher predicted hospital mortality.

Sex
Age (years)
Heart Rate (bpm)
MAP (mmHg)
Temperature (°C)
Respiratory Rate (/min)
PaO₂ (mmHg)
A-aDO₂ (mmHg)
Arterial pH
pCO₂ (mmHg)
Sodium (mEq/L)
BUN (mg/dL)
Creatinine (mg/dL)
Urine Output (mL/24h)
Glucose (mg/dL)
Albumin (g/dL)
Bilirubin (mg/dL)
Hematocrit (%)
WBC (×10³/µL)
GCS (3–15)
Chronic Health / Comorbidities
Clinical Guidance

APACHE III is an ICU severity-of-illness score built from the worst physiologic values in the first 24 hours of admission, so it cannot be computed from a single set of vitals. Enter the most deranged value recorded for each variable during that window.

The total (0–299) reflects acute physiology points across 17 variables, an age modifier, and chronic health/comorbidity flags. Higher scores indicate greater physiologic derangement and higher predicted hospital mortality. Use the score for ICU benchmarking and research stratification — not as the sole basis for individual treatment decisions.

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How to Use

Enter the values for the patient or scenario you are assessing. Calculate the APACHE III score, an ICU severity-of-illness measure that sums acute physiology points across 17 variables, an age modifier, and chronic health/comorbidity flags. Total score ranges 0–299, with higher scores indicating greater physiologic derangement and higher predicted hospital mortality. Use the apache iii score result to inform your clinical assessment.

Frequently Asked Questions