What MAP target is recommended in septic shock?

Standard MAP target ≥65 mmHg in septic shock; SEPSISPAM trial: MAP 80-85 mmHg in chronic hypertensives reduced renal replacement therapy (but increased atrial fibrillation); individualized MAP target based on patient history is best practice.

How is norepinephrine dose calculated?

Norepinephrine dose in μg/kg/min; standard range 0.01-3.3 μg/kg/min; mix concentration varies by protocol (4-32 mg in 250 mL NS); titrate by 0.01-0.05 μg/kg/min every 5-15 minutes to achieve MAP target.

When should vasopressin be added to norepinephrine?

Vasopressin 0.03-0.04 U/min can be added at NE doses ≥0.2-0.25 μg/kg/min to provide NE-sparing effect; VASST trial showed similar mortality but reduced NE requirements; doses >0.03-0.04 U/min not recommended (cardiac ischemia risk).

What peripheral MAP target for patients with CKD stage 4-5?

For patients with CKD (especially advanced stages) and chronic hypertension, higher MAP targets (70-80 mmHg) may preserve renal perfusion; conversely, high MAP targets in distributive shock increase cardiac afterload.

How should the transition from MAP 65 to lower dosing be managed?

Vasopressor weaning: reduce by 0.05 μg/kg/min every 15-30 min when MAP consistently >65-70 with improving clinical status; avoid rapid withdrawal as vasoplegic shock may have delayed vasomotor tone recovery.

Mean Arterial Pressure Target Calculator for ICU Vasopressor Management

Determines optimal MAP target in septic shock based on chronic hypertension, CKD stage, and age, with calculation of vasopressor doses (norepinephrine, vasopressin, phenylephrine) needed to achieve target MAP.

Weight

Height

Clinical Guidance

BMI is a screening measure of body size, not a direct measure of body fat. The standard WHO categories are underweight (<18.5), normal (18.5–24.9), overweight (25–29.9), and obese (≥30).

BMI can overestimate body fat in athletes with high muscle mass and underestimate it in older adults with low muscle mass. Interpret it alongside waist circumference and clinical context rather than as a standalone diagnosis.

⚕ Clinical Disclaimer: These calculators are for educational and reference purposes only. Always verify results with qualified clinical judgment and current clinical guidelines. Do not use as a sole basis for medical decisions.

How It Works

Each component has a specific meaning:

Chronic hypertension — The chronic hypertension recorded for the patient or scenario being assessed.
CKD stage — The ckd stage recorded for the patient or scenario being assessed.
Age — The age recorded for the patient or scenario being assessed.

Note: Interpret the map target icu result against the clinical thresholds and context described above.

How to Use

Enter the chronic hypertension, CKD stage, age for the patient or scenario you are assessing. Determines optimal MAP target in septic shock based on chronic hypertension, CKD stage, and age, with calculation of vasopressor doses (norepinephrine, vasopressin, phenylephrine) needed to achieve target MAP. Use the map target icu result to inform your clinical assessment.

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