Apply edoxaban dose reduction criteria for VTE treatment (60 mg to 30 mg daily) and AF: CrCl 15–50 mL/min, body weight ≤60 kg, or concomitant P-gp inhibitors. Unique: better at higher CrCl than lower.
Enter the values for the scenario you are assessing. Apply edoxaban dose reduction criteria for VTE treatment (60 mg to 30 mg daily) and AF: CrCl 15–50 mL/min, body weight ≤60 kg, or concomitant P-gp inhibitors. Unique: better at higher CrCl than lower. Use the edoxaban dose reduction result to inform your calculation.