What does RIFLE stand for?

RIFLE: Risk (Cr x1.5 or GFR decrease 25%), Injury (Cr x2 or GFR decrease 50%), Failure (Cr x3 or GFR decrease 75% or Scr >= 4 mg/dL with acute rise), Loss (complete loss of function > 4 weeks), ESKD (end-stage kidney disease > 3 months).

How does RIFLE compare to AKIN and KDIGO?

All three classify AKI severity. RIFLE uses GFR reduction, AKIN uses absolute creatinine rise (>= 0.3 mg/dL), KDIGO merged both approaches. Studies show KDIGO captures more AKI events and better predicts outcomes.

What are the urine output criteria for RIFLE?

Risk: UO < 0.5 mL/kg/h for 6h. Injury: UO < 0.5 mL/kg/h for 12h. Failure: UO < 0.3 mL/kg/h for 24h or anuria for 12h. Either creatinine or urine output criterion suffices.

RIFLE Criteria for Acute Kidney Injury

Classify AKI using RIFLE criteria: Risk (Cr x1.5 or GFR -25%), Injury (Cr x2 or GFR -50%), Failure (Cr x3 or GFR -75%), Loss (complete loss > 4 weeks), ESKD (> 3 months).

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Frequently Asked Questions

What does RIFLE stand for?

How does RIFLE compare to AKIN and KDIGO?

What are the urine output criteria for RIFLE?