What are DAPSA disease activity thresholds?

DAPSA remission ≤4; low disease activity 4-14; moderate 14-28; high >28; DAPSA is the preferred outcome measure for peripheral joint disease in psoriatic arthritis in EULAR and GRAPPA guidelines.

What joints are counted in DAPSA for PsA?

DAPSA uses 68-joint tender count (TJC68) and 66-joint swollen count (SJC66) to capture all affected joints; dactylitic digits are counted as individual joints; standard 28-joint counts are not sufficient for PsA.

Does DAPSA capture all PsA disease domains?

DAPSA captures peripheral joints only; does not assess axial disease (use BASDAI/ASDAS), enthesitis (MASES score), dactylitis, or skin (PASI/IGA); a minimal disease activity (MDA) composite encompasses all five domains.

What is Minimal Disease Activity (MDA) in PsA?

MDA requires 5 of 7 criteria: TJC ≤1, SJC ≤1, PASI ≤1 or BSA ≤3%, patient pain VAS ≤15, PtGA ≤20, HAQ ≤0.5, tender entheseal points ≤1; Very Low Disease Activity (VLDA) requires all 7.

Which biologics are approved specifically for psoriatic arthritis?

TNFi: adalimumab, certolizumab, etanercept, golimumab, infliximab; IL-12/23: ustekinumab; IL-17A: secukinumab, ixekizumab; IL-23: guselkumab, risankizumab; JAKi: upadacitinib, tofacitinib; PDE4i: apremilast.

DAPSA (Disease Activity in Psoriatic Arthritis) Calculator

Calculates DAPSA for psoriatic arthritis using tender joint count, swollen joint count, patient pain VAS, patient global VAS, and CRP, with remission threshold for biologic tapering decisions.

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